MovDisordV3, Main, Exploration, bibRecord, 003006

Asymmetrical ventricular enlargement in Parkinson's disease

Identifieur interne : 003006 ( Main/Exploration ); précédent : 003005; suivant : 003007

Asymmetrical ventricular enlargement in Parkinson's disease

Auteurs : Xuemei Huang [États-Unis] ; Yueh Z. Lee [États-Unis] ; Martin Mckeown [Canada] ; Guido Gerig [États-Unis] ; Hongbin Gu [États-Unis] ; Weili Lin [États-Unis] ; Mechelle M. Lewis [États-Unis] ; Sutapa Ford [États-Unis] ; Alexander I. Tröster [États-Unis] ; Daniel R. Weinberger [États-Unis] ; Martin Styner [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2007-08-15.

RBID : ISTEX:807B172D711C2C63D8A881FFEE18B74EB5E50CAC

English descriptors

KwdEn :
- Adult, Cerebral Ventricles (pathology), Diseases in Twins, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Parkinson Disease (pathology), Parkinson's disease, Twin Studies as Topic, motor impairment, ventricle, volume asymmetry.
MESH :
- pathology : Cerebral Ventricles, Parkinson Disease.
- Adult, Diseases in Twins, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Twin Studies as Topic.

Abstract

Parkinson's disease (PD) typically manifests with asymmetric motor symptom onset. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with cognitive decline in PD, but not with motor symptom asymmetry. Asymmetrical ventricular enlargement on magnetic resonance images was explored in a monozygotic twin pair discordant for PD and in nine healthy monozygotic twin pairs. The left–right lateral ventricular volumetric difference of the PD‐twin was greater than that of his twin and all other healthy twins, with the larger ventricle observed contralateral to the more symptomatic side. Moreover, the lateral ventricle asymmetry difference between twin pairs was significantly higher for the discordant PD‐twin pair than for the healthy twin pairs. This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study. © 2007 Movement Disorder Society

Url:

https://api.istex.fr/document/807B172D711C2C63D8A881FFEE18B74EB5E50CAC/fulltext/pdf

DOI: 10.1002/mds.21626

Affiliations:

Le document en format XML

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<author><name sortKey="Lee, Yueh Z" sort="Lee, Yueh Z" uniqKey="Lee Y" first="Yueh Z." last="Lee">Yueh Z. Lee</name>
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<author><name sortKey="Mckeown, Martin" sort="Mckeown, Martin" uniqKey="Mckeown M" first="Martin" last="Mckeown">Martin Mckeown</name>
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<author><name sortKey="Gerig, Guido" sort="Gerig, Guido" uniqKey="Gerig G" first="Guido" last="Gerig">Guido Gerig</name>
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<author><name sortKey="Gu, Hongbin" sort="Gu, Hongbin" uniqKey="Gu H" first="Hongbin" last="Gu">Hongbin Gu</name>
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<author><name sortKey="Lin, Weili" sort="Lin, Weili" uniqKey="Lin W" first="Weili" last="Lin">Weili Lin</name>
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<author><name sortKey="Lewis, Mechelle M" sort="Lewis, Mechelle M" uniqKey="Lewis M" first="Mechelle M." last="Lewis">Mechelle M. Lewis</name>
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<author><name sortKey="Ford, Sutapa" sort="Ford, Sutapa" uniqKey="Ford S" first="Sutapa" last="Ford">Sutapa Ford</name>
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<author><name sortKey="Troster, Alexander I" sort="Troster, Alexander I" uniqKey="Troster A" first="Alexander I." last="Tröster">Alexander I. Tröster</name>
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<author><name sortKey="Weinberger, Daniel R" sort="Weinberger, Daniel R" uniqKey="Weinberger D" first="Daniel R." last="Weinberger">Daniel R. Weinberger</name>
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<author><name sortKey="Styner, Martin" sort="Styner, Martin" uniqKey="Styner M" first="Martin" last="Styner">Martin Styner</name>
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<author><name sortKey="Mckeown, Martin" sort="Mckeown, Martin" uniqKey="Mckeown M" first="Martin" last="Mckeown">Martin Mckeown</name>
<affiliation wicri:level="1"><country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine (Neurology), Pacific Parkinson's Research Centre, University of British Columbia (UBC), University Hospital, Vancouver, British Columbia</wicri:regionArea>
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<author><name sortKey="Styner, Martin" sort="Styner, Martin" uniqKey="Styner M" first="Martin" last="Styner">Martin Styner</name>
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<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
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<term>Diseases in Twins</term>
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<front><div type="abstract" xml:lang="en">Parkinson's disease (PD) typically manifests with asymmetric motor symptom onset. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with cognitive decline in PD, but not with motor symptom asymmetry. Asymmetrical ventricular enlargement on magnetic resonance images was explored in a monozygotic twin pair discordant for PD and in nine healthy monozygotic twin pairs. The left–right lateral ventricular volumetric difference of the PD‐twin was greater than that of his twin and all other healthy twins, with the larger ventricle observed contralateral to the more symptomatic side. Moreover, the lateral ventricle asymmetry difference between twin pairs was significantly higher for the discordant PD‐twin pair than for the healthy twin pairs. This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study. © 2007 Movement Disorder Society</div>
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Movement Disorders (revue)

Asymmetrical ventricular enlargement in Parkinson's disease

Asymmetrical ventricular enlargement in Parkinson's disease

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.